Midway via his job, Cees Dekker reinvented himself. Following decades of hardcore physics, he shifted his target to ‘nanobiology’ within the change of your millennium. A phrase he coined himself, for a make a difference of point.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Within the exact time, the group of Paul McEuen, who was then based for the University of California, Berkeley, confirmed related outcomes on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed applying scanning tunnelling spectroscopy experiments.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial cell division; and to start with ever analyze on the dynamics DNA supercoils and the discovery of supercoil hopping
Instance (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim with the pore is highlighted in crimson, and a 3D rendering with the motion of your DNA rod is shown.
We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular level. Our projects include the following:
Researching DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
‘You should not just take into consideration the queries of tomorrow, but in addition take into account the inquiries on the day right after tomorrow’
Dekker started off his investigation on single carbon nanotubes in 1993 when he build a whole new line of study to check electrical transportation via one natural molecules between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was attained in a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography approaches had been utilized to show that these nanotubes are quantum wires at The one-molecule degree, with outstanding Bodily Attributes.
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Afterwards we spoke again briefly because Dekker felt that our dialogue of his religion speedily became purely philosophical, whereas In addition it concretely allows him in his get the job done.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of https://www.ceesdekker.net just one wire bridging two electrodes
‘I'm pushed by wonder and concerns. On a material stage I obtain responses in physics, but I experience my deepest joy with God. That faith also drives my science and how I manage men and women.
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